A cryoinjury model in neonatal mice for cardiac translational and regeneration research
نویسندگان
چکیده
منابع مشابه
Ezh2 is not required for cardiac regeneration in neonatal mice
The neonatal mouse heart has the remarkable capacity to regenerate lost myocardium within the first week of life. Neonatal cardiomyocytes re-express fetal genes that control cell proliferation after injury to promote regeneration. The loss of regenerative capacity of the heart one week after birth coincides with repression of a fetal transcriptional program coordinated by epigenetic regulators....
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ژورنال
عنوان ژورنال: Nature Protocols
سال: 2016
ISSN: 1754-2189,1750-2799
DOI: 10.1038/nprot.2016.031